DNA-seq

DNA-seq

DNA-seq

Preparing a high-quality DNA library is the first step in a successful DNA sequencing experiment. When starting with DNA of limited quantity or varying quality, the library preparation method must be accurate and efficient, avoiding purification steps that reduce sample recovery. Meeting these requirements for a wide range of applications, our SMARTer DNA sequencing portfolio features single-tube workflows for challenging samples such as single cells, cell-free DNA, or FFPE DNA.

  • The ThruPLEX DNA-seq kit can be used in any DNA-seq, RNA-seq, or ChIP-seq application and offers robust, targeted sequencing performance with all leading target enrichment platforms. The ThruPLEX Plasma-seq kit is optimized for cell-free DNA input. The ThruPLEX Tag-seq kit integrates unique molecular tags to allow detection of low-frequency alleles.
  • The PicoPLEX WGA Kit and PicoPLEX DNA-seq Kit are the gold standards for CNV and aneuploidy detection from single-cell and picogram-level inputs.
DNA-seq
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  1. PicoPLEX Gold Single Cell DNA-seq Kit

    Optimised for the reproducible detection of copy number variants (CNVs), single nucleotide variants (SNVs), indels, and small structural variants

  2. ThruPLEX DNA-Seq Kit

    Generate DNA libraries from as little as 50 pg of DNA, whilst providing up to 384 indexes for multiplexing

  3. ThruPLEX Plasma-Seq Kit

    Optimised for cell-free DNA to maximise library complexity and to preserve the GC representation of the input sample

  4. ThruPLEX Tag-seq Kit

    Combines molecular tags with ThruPLEX chemistry to construct molecularly tagged and sample-indexed Illumina NGS libraries

  5. DNA HT Dual Index Kits

    Dual-indexed PCR primers for amplification of indexed Illumina-compatible NGS libraries

  6. DNA Single Index Kits

    Single-indexed PCR primers for amplification of indexed Illumina-compatible NGS libraries

  7. DNA Unique Dual Index Kits

    Unique dual-indexed PCR primers for amplification of indexed Illumina-compatible NGS libraries

  8. ThruPLEX DNA-Seq HV

    Generate high-complexity DNA libraries from standard samples and challenging sample such as FFPE and cell-free plasma DNA

  9. ThruPLEX Tag-Seq HV

    Offers added power in correcting for amplification and sequencing errors—key advantages when detecting low-frequency variants

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