Antibody purification resins—an alternative to Protein A
TAC is a powerful and simple method for the purification of proteins—in particular, immunoglobulins. It is an economical alternative to Protein A for purifying antibodies from whole serum and tissue culture. In comparison to Protein A-based immunoadsorbents, thiophilic adsorbents have a broader affinity for immunoglobulins. Further, more than 99% of total proteins are recovered using a thiophilic adsorbent, in comparison to less than 92% for phenyl and 75% for octyl agarose adsorbents.