Deletions, insertions, translocations, and inversions of genes
Cre-mediated recombination has been widely used to carry out deletions, insertions, translocations, and inversions of genes at specific sites in the genome. We offer products to facilitate AAV- or gesicle-based delivery of Cre recombinase for Cre-lox recombination-based experiments. In addition, we offer Cre RLPs (RNA lentiviral particles), biologically active Cre mRNA packaged in nonintegrating, virus-like particles, which enable transient Cre expression for in vitro or in vivo applications.
Cre Recombinase Gesicles provide a fast, easy method for efficient genome modification without the use of nucleic acids. Gesicles show excellent performance in most cell types, thus expanding research possibilities....