Pathway Profiling Vectors
Our pathway profiling systems provide a means to assess cell signaling pathway activation in vivo. These systems consist of sets of vectors that each contain a distinct cis-acting enhancer element upstream of a reporter gene. A single transfection experiment provides a profile of the transcription factors that are affected by a given stimulus, drug candidate, or gene product of interest.
Profile multiple signal transduction pathways
Most of the cis-acting enhancer elements included in our transcription factor systems are regulated by more than one transcription factor so that multiple signal transduction pathways can be monitored. Reporter expression indicates that a transactivator present in the cell has bound the enhancer element in one of the TransFactor vectors, indicating that a particular signaling pathway or pathways has been activated.
Two reporters available—luciferase & SEAP