Uni-Link AminoModifier
Uni-Link AminoModifier
Brand: Takara Bio.
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Uni-Link AminoModifier
Uni-Link AminoModifier is a cyanoethyl phosphoramidite that allows you to directly incorporate a primary amine onto the 5' end of an oligonucleotide using automated synthesis. Label-ON reagents provide an efficient way to directly label oligonucleotides with various reporter molecules. All Label-On Reagents possess the patented 2-aminobutyl-1,3-propanediol (ABPD) backbone, which offer distinct benefits.
Overview
- Incorporate single or multiple labels during oligonucleotide synthesis
- Place labels at the 5' end, internally, or at the 3' end
- Maintain natural 3-carbon internucleotide phosphate distance
- Obtain very high coupling efficiencies on any commercially available synthesizer
Applications
- Oligo labeling (reagents)
- Nucleic acid modifications
- Nucleic acid chemistry (reagents)
- Nucleic acid labeling (reagents)
- Nucleic acid synthesis (reagents)
The molecular backbone of Label-ON Reagents
The molecular backbone of Label-ON Reagents.
Nelson, P.S., Kent, M., & Muthini, S. Oligonucleotide labeling methods 3. Direct labeling of oligonucleotides employing a novel, non-nucleosidic, 2-aminobutyl-1,3-propanediol backbone. Nucleic Acids Res. 20, 6253-6259 (1992).
Nelson, P. & Muthini, S. OligoTechniques 1, 1-4 (1993).
Nelson, P., et al. OligoTechniques 1, 5-7 (1993).
Nelson, P. & Muthini, S. Biomedical Products 18, 40 (1993).
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The molecular backbone of Label-ON Reagents
The molecular backbone of Label-ON Reagents.
