PARP Monoclonal Antibody
PARP Monoclonal Antibody
Brand: Takara Bio.
In stock
SKU
PARP Monoclonal Antibody
Clone C-2-10 recognizes 116-kDa native poly (ADP-ribose) polymerase (PARP) and the 85-kDa apoptosis-related cleavage product. This mouse monoclonal antibody cross-reacts with human, monkey, hamster, rat, and mouse. PARP is a target of proteolytic cleavage by the ICE-family proteases CPP32 and Mch2α during the early stages of apoptosis. PARP cleavage is an early indicator of apoptosis. Native PARP has a molecular weight of 116 kDa; cleavage yields fragments of 85 kDa and 25 kDA.
Overview
- PARP monoclonal antibody recognizes native and cleaved poly(ADP-ribose) polymerase or PARP (PARP cleavage is an early indicator of apoptosis)
Applications
- Use the PARP antibody to detect the early stages of apoptosis via western blotting, immunocytochemistry, or ELISA
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