Human Stem Cell-derived Cardiomyocytes
Human Stem Cell-derived Cardiomyocytes
Brand: Takara Bio.
In stock
SKU
Human Stem Cell-derived Cardiomyocytes
Overview
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Electrophysiological profile highly resembling adult human primary cardiomyocytes
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Respond as expected to cardiac stimuli
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Derived with a robust, efficient cardiac differentiation protocol, without genetic engineering or selection
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Cells are provided with basal medium for thawing and culture
Cellartis cardiomyocytes are a highly homogeneous population of cardiomyocytes derived from human induced pluripotent stem (iPS) cells (ChiPSC22). The iPS cells have been differentiated into spontaneously beating cardiomyocytes in vitro. These cells have been dissociated into a single-cell suspension and frozen in vials. The Cellartis Cardiomyocytes (from ChiPSC22) Kit contains one vial of cardiomyocytes (>3 x 106 viable cells), one bottle of Cellartis CM Thawing Base, and one bottle of Cellartis CM Culture Base.
Cellartis cardiomyocytes are a highly homogeneous population of cardiomyocytes derived from human induced pluripotent stem (iPS) cells (ChiPSC22). The iPS cells have been differentiated into spontaneously beating cardiomyocytes in vitro. These cells have been dissociated into a single-cell suspension and frozen in vials. The Cellartis Cardiomyocytes (from ChiPSC22) Kit contains one vial of cardiomyocytes (>3 x 106 viable cells), one bottle of Cellartis CM Thawing Base, and one bottle of Cellartis CM Culture Base.
Overview
-
Electrophysiological profile highly resembling adult human primary cardiomyocytes
-
Respond as expected to cardiac stimuli
-
Derived with a robust, efficient cardiac differentiation protocol, without genetic engineering or selection
-
Cells are provided with basal medium for thawing and culture
Applications
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Safety pharmacology
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Cardiotoxicity testing
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Discovery of novel cardiac drug targets
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Phenotypic screening
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High-content analysis (HCA)
Components
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1 vial Cellartis cardiomyocytes (>3 x 106 viable cells)
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1 bottle Cellartis CM Thawing Base (32 ml)
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1 bottle Cellartis CM Culture Base (90 ml)
Cellartis Cardiomyocytes (from ChiPSC22) respond in a dose-dependent manner to hERG blocker E4031 as measured by MEA (MED64 AlphaMED MEA system)
Cellartis Cardiomyocytes (from ChiPSC22) respond in a dose-dependent manner to hERG blocker E4031 as measured by MEA (MED64 AlphaMED MEA system). BL = baseline and EAD = early after depolarization.
Cellartis Cardiomyocytes (from ChiPSC22) express cardiomyocyte markers, including cTroponin (red)
Cellartis Cardiomyocytes (from ChiPSC22) express cardiomyocyte markers, including cTroponin (red). Nuclei are labelled with DAPI (blue). F-actin is labeled with Phalloidin (green).
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Cellartis Cardiomyocytes (from ChiPSC22) respond in a dose-dependent manner to hERG blocker E4031 as measured by MEA (MED64 AlphaMED MEA system)
Cellartis Cardiomyocytes (from ChiPSC22) respond in a dose-dependent manner to hERG blocker E4031 as measured by MEA (MED64 AlphaMED MEA system). BL = baseline and EAD = early after depolarization.
Cellartis Cardiomyocytes (from ChiPSC22) express cardiomyocyte markers, including cTroponin (red)
Cellartis Cardiomyocytes (from ChiPSC22) express cardiomyocyte markers, including cTroponin (red). Nuclei are labelled with DAPI (blue). F-actin is labeled with Phalloidin (green).
