Cloned alpha 2,3-Sialidase
Cloned alpha 2,3-Sialidase
Brand: Takara Bio.
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Cloned alpha 2,3-Sialidase
This sialidase has a 260-fold kinetic preference for the α2,3 sialyl linkage. The enzyme efficiently cleaves sialyl groups from glycoproteins and glycolipids. It may not release sialic acid from O-linked oligosaccharides on glycoproteins.
Overview
- This sialidase has a 260-fold kinetic preference for the alpha 2,3 sialyl linkage
- The enzyme efficiently cleaves sialyl groups from glycoproteins and glycolipids
- The enzyme may not release sialic acid from O-linked oligosaccharides on glycoproteins
Source
E. coli (cloned from Salmonella typhimurium LT2)
Hoyer, L.L. et al. Cloning, sequencing and distribution of the Salmonella typhimurium LT2 sialidase gene, nanH, provides evidence for interspecies gene transfer. Mol. Microbiol. 6, 873–884 (1992).
Hoyer, L.L. et al. Purification and properties of cloned Salmonella typhimurium LT2 sialidase with virus-typical kinetic preference for sialyl alpha 2-3 linkages J. Biochem. 110, 462–467 (1991).
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