BIC System
The Brevibacillus Expression System is an efficient system for producing secreted proteins and is ideal for eukaryotic recombinant protein expression. Brevibacillus choshinensis is a gram-positive bacterium well-suited for heterologous protein expression and is capable of producing high yields of active protein.
Overview
- Efficient production of secreted or intracellular recombinant target proteins
- Negligible amounts of extracellular protease—products remain intact in culture medium
- Unlike E. coli, no endotoxins
- Proteins are produced in active form
- Easy to culture, handle, and sterilize
Overview of the Brevibacillus in vivo Cloning (BIC) method
Overview of the Brevibacillus in vivo Cloning (BIC) method.
pBIC vector map
pBIC vector map.
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Overview of the Brevibacillus in vivo Cloning (BIC) method
Overview of the Brevibacillus in vivo Cloning (BIC) method.
pBIC vector map
pBIC vector map.
