The pQCXIN Retroviral Vector is a self-inactivating retroviral Q expression vector that is optimized to eliminate promoter interference from the upstream LTR in the integrated provirus. It expresses a target gene along with the gene for the neomycin resistance marker from a single, bicistronic message. The CMV promoter present in the 5′ LTR produces high viral titers in standard packaging cell lines. A deletion in the 3′ LTR provides the self-inactivating feature after reverse transcription of the expression cassette. This vector is useful for applications in which high titers and high-level gene expression are desired.
Overview
- Retroviral vectors designed for high retroviral titers and high expression of your transgene
- Compatible with all Takara Bio brand retroviral packaging cell lines
- Vector information is listed on our vector information pages
- Fluorescent protein, MSCV, and tetracycline-inducible retroviral vectors are described elsewhere
