pLNCX2 is designed for retroviral gene delivery and expression. Upon transfection into a packaging cell line, pLNCX2 can transiently express, or integrate and stably express, a transcript containing the Ψ viral packaging signal, a selectable marker, and the geneof interest, which is cloned into the MCS under the control of the immediate early promoter of human cytomegalovirus (PCMV). The 5′ viral LTR drives expression of the neomycin resistance gene for antibiotic selection in eukaryotic cells.
Overview
- Retroviral vectors designed for high retroviral titers and high expression of your transgene
- Compatible with all Takara Bio brand retroviral packaging cell lines
- Vector information is listed on our vector information pages
- Fluorescent protein, MSCV, and tetracycline-inducible retroviral vectors are described elsewhere
