The DmrC Polyclonal Antibody was raised in rabbit and recognizes as little as 20–40 ng of DmrC-tagged fusion protein expressed using any iDimerize Inducible Heterodimer System. The antibodies are also able to detect fusions created using ARGENT regulation systems: DmrA is identical to wild type FKBP12, DmrB is identical to the F36V mutant of FKBP12, DmrC is identical to the T82L mutant of FRB.
Overview
- The DmrB and DmrA domains are highly homologous, so the antibodies cross-react with each others’ domains
- The anti-DmrC antibody does not cross-react with the other domains
- Detection of DmrB domains used for iDimerize Homodimer Systems
- Detection of DmrA and DmrC domains used for iDimerize Heterodimer Systems
- DmrB antibody can be used for detection of DmrD domains used for the Reverse Dimerization Systems
- DmrA is identical to wild type FKBP12
- DmrB is identical to the F36V mutant of FKBP12
- DmrC is identical to the T82L mutant of FRB
Source
- DmrA and DmrB monoclonal antibodies: mouse
- DmrC polyclonal antibody: rabbit
