This sialidase has a 260-fold kinetic preference for the α2,3 sialyl linkage. The enzyme efficiently cleaves sialyl groups from glycoproteins and glycolipids. It may not release sialic acid from O-linked oligosaccharides on glycoproteins.
Overview
- This sialidase has a 260-fold kinetic preference for the alpha 2,3 sialyl linkage
- The enzyme efficiently cleaves sialyl groups from glycoproteins and glycolipids
- The enzyme may not release sialic acid from O-linked oligosaccharides on glycoproteins
Source
E. coli (cloned from Salmonella typhimurium LT2)
