Cellartis Power Primary HEP Medium is specially formulated to enable the long-term maintenance—cells are viable and maintain functionality for four weeks—of cryopreserved, plateable human primary hepatocytes in conventional 2D cultures. This medium further simplifies culturing of hepatocytes with a weekend-free feeding schedule.
Overview
- Extended culture time—keeps primary hepatocytes viable and metabolically active for four weeks in culture as measured by CYP activities, albumin secretion, and CYP induction capabilities
- Long-term compound incubation—supports incubations of up to 10 days without medium change, enabling intrinsic clearance studies of low clearance compounds
- Flexible format—delivered frozen; may be aliquoted and refrozen
- Convenient workflow—allows a weekend-free feeding schedule [with media changes every other day (Mon, Wed, Fri) instead of daily] and eliminates complicated overlays or sandwich cultures
- Custom formulations—we offer customization of this product to better serve your research needs.
Applications
- Liver disease modeling
- Hepatotoxicity assessment
- Chronic toxicity
- Intrinsic clearance studies
