Cellartis Hepatocyte Maintenance Medium are used for prolonged maintenance of hepatocyte cells in 2D culture, derived using Cellartis Hepatocyte Differentiation Kit (Cat. No. Y30050) or Cellartis iPS Cell to Hepatocyte Differentiation System (Cat. No. Y30055).
The Cellartis iPS Cell to Hepatocyte Differentiation System is a complete system for differentiation of human induced pluripotent stem (iPS) cells to hepatocytes via definitive endoderm (DE). This kit includes the Cellartis DEF-CS Culture System for expansion of undifferentiated iPS cells, the Cellartis Definitive Endoderm Differentiation Kit for differentiation to DE cells, and the Cellartis Hepatocyte Differentiation Kit for subsequent differentiation to hepatocytes.
Overview
- Highly reproducible, robust system—the exact same protocol has been shown to work across 25 different iPS cell lines, so there’s no need to optimize for your lines
- Ideal for drug metabolism and safety studies—consistently generate panels of >90% pure, functional, hiPS cell-derived hepatocytes with diverse genetic backgrounds
- Customized starting materials—start with any disease-relevant iPS cell lines and create accurate liver disease models
- Ready for personalized medicine—make patient-specific, disease-specific cells for therapeutic applications
- Extended experimental window—hepatocytes can be used for a minimum of 11 days for functional tests
Components
- Cellartis DEF-CS 100 Culture System (Cat. # Y30020, not sold separately)
- Cellartis Definitive Endoderm Differentiation Kit (Cat. # Y30030, not sold separately)
- Cellartis Hepatocyte Differentiation Kit (Cat. # Y30050)
