Calpain inhibitor: Calpastatin protease inhibitor
Calpastatin is an endogenous protease inhibitor that acts specifically on calpain (a calcium-dependent cysteine protease). It consists of four repetitive sequences comprising of 120 to 140 amino acid residues, and an N-terminal non-homologous sequence(L). This product is obtained from highly purified domain I of human calpastatin, comprising of 135 amino acids (MW 14,000), which is produced by genetic recombination technique.
Applications
- Calpain protease inhibition
