BIC System

Additional information

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The Brevibacillus Expression System is an efficient system for producing secreted proteins and is ideal for eukaryotic recombinant protein expression. Brevibacillus choshinensis is a gram-positive bacterium well-suited for heterologous protein expression and is capable of producing high yields of active protein.

Overview

  • Efficient production of secreted or intracellular recombinant target proteins
  • Negligible amounts of extracellular protease—products remain intact in culture medium
  • Unlike E. coli, no endotoxins
  • Proteins are produced in active form
  • Easy to culture, handle, and sterilize

Overview of the Brevibacillus in vivo Cloning (BIC) method

Overview of the Brevibacillus in vivo Cloning (BIC) method

Overview of the Brevibacillus in vivo Cloning (BIC) method.

pBIC vector map

pBIC vector map

pBIC vector map.